Sodium Phenylbutyrate
To decrease pruritis/itch. Limited reports on the efficacy in PFIC but has been reported to both improve itch (PFIC 1 and 2 patients) and improve liver biochemistry (PFIC2 patients only).
Has been used in PFIC to correct mis-trafficking of PFIC proteins within the liver cell.
Protein trafficking refers to the transport of proteins to where they need to be.
Your Experience
Matters
Recorded: 1
Community
Experiences
PFIC patients & the community have
reported the following experiences:
Benefits
- Patients report a small reduction of itch with resulting patient quality of life.
Burdens
- Can be expensive.
Impacted Areas
of Patient Life
Of the six main areas mainly affected by PFIC, patients & the community have identified the areas impacted by this medication.
Resources
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do so by visiting our Resource page.
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