Cholestyramine
Binds to bile acids in the intestine, causing the bound bile acids to be excreted in the stool along with the resin (and preventing the bile from being reabsorbed into the liver). Historically, cholestyramine has primarily been used to treat high cholesterol.
To decrease pruritis/itch.
Your Experience
Matters
Recorded: 4
Community
Experiences
PFIC patients & the community have
reported the following experiences:
Benefits
- Some patients reported no reduction of itch.
- Some patients reported a small reduction of itch, which went together with somewhat better sleep and patient quality of life.
- Can reduce diarrhea and improve stool consistency.
- According to the parent reports we collected so far cholestyramine has been prescribed in case of FIC1 and BSEP deficiency (PFIC 1 and 2).
Burdens
- Can cause intermittent colics and diarrhea.
- Can interact with other medicines.
Impacted Areas
of Patient Life
Of the six main areas mainly affected by PFIC, patients & the community have identified the areas impacted by this medication.
Resources
If you’d like to learn more you can
do so by visiting our Resource page.
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