Medications

Cholestyramine

About this Treatment
  • Binds to bile acids in the intestine, causing the bound bile acids to be excreted in the stool along with the resin (and preventing the bile from being reabsorbed into the liver). Historically, cholestyramine has primarily been used to treat high cholesterol.

  • To decrease pruritis/itch.

  • How it Works
  • Reasons For Prescribing

Your Experience
Matters

Date Last Updated: 07/26/2024
Community Experiences
Recorded:
4

Community
Experiences

PFIC patients & the community have
reported the following experiences:

Benefits

  • Some patients reported no reduction of itch.
  • Some patients reported a small reduction of itch, which went together with somewhat better sleep and patient quality of life.
  • Can reduce diarrhea and improve stool consistency.
  • According to the parent reports we collected so far cholestyramine has been prescribed in case of  FIC1 and BSEP deficiency (PFIC 1 and 2).

Burdens

  • Can cause intermittent colics and diarrhea.
  • Can interact with other medicines.

Impacted Areas
of Patient Life

Of the six main areas mainly affected by PFIC, patients & the community have identified the areas impacted by this medication.

Itch
Patient Quality of Life
Family Quality of Life
Sleep Quality
Reduction of Diarrhea
Malnutrition

Resources

If you’d like to learn more you can
do so by visiting our Resource page.

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