Ursodiol
To decrease pruritis/itch. To decrease cholestasis (cholestasis is the slowing or stalling of bile flow through your biliary system). To improve bile flow or modify the bile acid pool.
Ursodiol can also prevent stone formation, a potential complication of PFIC 2 (BSEP) and PFIC 3 (MDR3) disease.
Ursodiol is synthetic (artificial) bile acid consisting primarily of deoxycholic acid. It increases bile secretion (discharge) and reduces absorption of hydrophilic (= water soluble) bile acids by the ileum. The ileum is a part of the small intestine.
Your Experience
Matters
Recorded: 5
Community
Experiences
PFIC patients & the community have
reported the following experiences:
Benefits
- Can reduce itch.
- Can improve eating, sleep quality, and patient and family quality of life.
- A parent reported itch reduction with the right dosage
Burdens
Impacted Areas
of Patient Life
Of the six main areas mainly affected by PFIC, patients & the community have identified the areas impacted by this medication.
Resources
If you’d like to learn more you can
do so by visiting our Resource page.
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