Rifampicin
Rifampicin – increases metabolism of circulating pruritogenic (itch generating) compounds and promotes their excretion in the urine. It may also alter the composition of bacteria in the intestine (microbiome), which may affect metabolism of pruritogenic (itch-producing) substances in the gut.
To decrease pruritis/itch.
Your Experience
Matters
Recorded: 7
Community
Experiences
PFIC patients & the community have
reported the following experiences:
Benefits
- Parents report a small reduction of itch, which was important to them.
- Parents report improvements of sleep and patient and family quality of life when itch is reduced.
- A parent reported that the reduction of itch occurred after 11 days.
Burdens
- Reduced effectiveness for itch over time can occur.
- Concerns about negative health effects related to long-term use of antibiotics.
- Parent reported red discoloration of urine and tears.
Impacted Areas
of Patient Life
Of the six main areas mainly affected by PFIC, patients & the community have identified the areas impacted by this medication.
Resources
If you’d like to learn more you can
do so by visiting our Resource page.
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