Odansetron
Blocks histamine. Histamine is a signaling molecule, sending messages between cells. Blocking histamine signaling can help to limit allergic reactions including itch. Histamine is not generally believed to be causative in PFIC, thus efficacy may be limited. Since histamine helps staying awake, using antihistamines can cause drowsiness.
To decrease pruritis/itch. Limited reports on possible efficacy in PFIC.
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Impacted Areas
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Of the six main areas mainly affected by PFIC, patients & the community have identified the areas impacted by this medication.
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